A Guide to Nutrition on GLP-1 Medications

Understanding Nutrition with GLP-1 Medications

GLP-1 receptor agonists (Glucagon-Like Peptide-1) are revolutionising weight management by impacting satiety, slowing gastric emptying, and influencing blood sugar regulation. While these medications are highly effective in promoting weight loss, they can also alter nutrient absorption and appetite, necessitating a thoughtful approach to nutrition and supplementation. The primary goals for individuals on GLP-1 medications should be to optimise nutrient intake, prevent deficiencies, support metabolic health, and preserve lean muscle mass.

Supplement Benefits At A Glance

Focus Area 1: Natural Weight Management & Metabolic Support

While GLP-1 medications are helpful for some, they’re not for everyone. Natural strategies may enhance weight management and metabolic health, when accompanied by a healthy diet and lifestyle.

• Weight Management with Metabolaid (Hibiscus and Lemon Verbena Extract): This patented blend has been studied for its role in weight management and metabolic health. Research suggests that components within Weight Management with Metabolaid may help improve satiety, reduce fat accumulation, and support healthy blood lipid profiles [1]. By incorporating such extracts, individuals may experience enhanced benefits alongside their healthy diet and exercise regimen.
  
  
• Green Tea Extract: Rich in catechins, particularly epigallocatechin gallate (EGCG), green tea is well-known for its thermogenic properties and potential to affect fat oxidation [2]. It may also contribute to improved insulin sensitivity, a crucial aspect of metabolic health for those managing weight.
  
  
• Cinnamon: Beyond its culinary uses, cinnamon has been investigated for its potential to support blood sugar control by affecting insulin sensitivity and mitigating glucose absorption [3]. For individuals on GLP-1s, which also impact blood sugar, cinnamon may offer complementary support.
  
  
• Multivitamin for Blood Sugar Management: A specialised multivitamin is essential. Look for formulations that include chromium, which plays a role in carbohydrate and lipid metabolism and may support insulin action [4]. Additionally, B vitamins are crucial for energy production, and vitamin D is important for overall metabolic health.
  

Focus Area 2: GLP-1 Users Guide: Prevention of Nutritional Deficiencies & Muscle Maintenance

Weight loss, especially rapid weight loss, can sometimes lead to nutrient deficiencies and muscle loss. Proactive strategies are vital to mitigate these risks.

Prevention of Nutritional Deficiencies

• Multivitamin with Energy-Supporting Nutrients: Due to reduced food intake and altered absorption, a high-quality multivitamin is paramount. Ensure it contains a comprehensive spectrum of B vitamins (B1, B2, B3, B5, B6, B7, B9, B12) for their critical role in energy metabolism [5]. Vitamins C and E, along with selenium and zinc, provide support against oxidative stress.
  
  
• Iron Supplement: Iron deficiency is a common concern, particularly in women and those with reduced red meat intake. Iron is essential for oxygen transport and energy production [6]. Regular monitoring of iron levels and appropriate supplementation under the guidance of a healthcare practitioner is important.
  

Muscle Maintenance

Preserving lean muscle mass during weight loss helps to maintain metabolic rate and functional strength.

• Creatine: This well-researched supplement supports muscle strength, power, and lean mass, particularly when combined with resistance training [7]. For individuals on GLP-1s, who may experience a decrease in overall food intake, creatine may help preserve muscle tissue.
  
  
• Branched-Chain Amino Acids (BCAAs): Leucine, isoleucine, and valine are essential amino acids that play a direct role in muscle protein synthesis [8]. Supplementing with BCAAs, especially around workouts, can help minimise muscle breakdown and promote recovery.
  
  
• Pea Protein: An excellent plant-based protein source, pea protein is rich in essential amino acids, including BCAAs. It contributes to satiety and supports muscle repair and growth, making it an ideal choice for increasing protein intake without adding excessive calories [9]. Aim for approximately 0.8-1.2 grams of protein per kilogram of ideal body weight daily.

Gut Support

GLP-1 medications can sometimes impact gut motility and microbiota. Supporting gut health is key for comfort and nutrient absorption.

• Fructooligosaccharides (FOS): FOS are soluble fibres that nourish beneficial gut bacteria [10]. A healthy gut microbiome is essential for digestion, nutrient absorption, and immune function.
  
  
• Daily Live Bacteria: Introducing a diverse live bacteria supplement may help maintain a balanced gut flora and supporting overall digestive health [11]. Look for strains like Lactobacillus and Bifidobacterium.

Bone Support

Weight loss, particularly rapid weight loss, can sometimes impact bone mineral density.

• Bone Support Formula: A comprehensive bone support formula should include calcium, vitamin D3, magnesium and vitamin K2. Calcium is the primary mineral for bone structure, vitamin D3 aids in calcium absorption, magnesium contributes to strong teeth & bones, and vitamin K2 helps direct calcium to the bones and away from arteries [12].
  

Hydration

Adequate hydration is fundamental for all bodily functions, especially during weight loss and when taking medications that can influence fluid balance.

• Magnesium Powder: Magnesium is an essential mineral involved in over 300 enzymatic reactions, including muscle and nerve function, blood glucose control, and blood pressure regulation [13]. It may also lessen muscle cramps and aid in bowel regularity, which can be beneficial with changes in diet. Using a magnesium powder stirred into liquid provides efficient absorption of the mineral and a hydrating drink.
  

Explore more: Support your wellbeing on GLP-1 medications with our specially selected product range. Find solutions for hair, skin, and nail health, nausea, and crucial omega 3s.

Final Thoughts

Navigating weight loss with GLP-1 medications offers a powerful opportunity for health transformation. By integrating a well-planned nutritional strategy that focuses on natural metabolic support, meticulous prevention of nutrient deficiencies, diligent muscle maintenance, robust gut health, and strong bone support, individuals can maximise the benefits of their medication while safeguarding their overall wellbeing. Always consult with a healthcare professional or a registered dietitian to tailor these recommendations to your specific needs and health profile.

Do you need expert advice? Contact our Nutrition Advisors with any questions you may have about managing healthy weight loss, diet and nutrition.

Frequently Asked Questions

What are the side effects of GLP-1s on digestion that diet can fix?

GLP-1 medications frequently cause side effects such as nausea, bloating, constipation, and slowed gastric emptying. Diet and targeted supplementation may help mitigate these issues by incorporating prebiotic fibres (like FOS) and daily probiotics to support gut motility, using magnesium powder to aid bowel regularity, and eating smaller, nutrient-dense meals to reduce gastrointestinal distress.

How much protein do I need while taking medications like Ozempic or Wegovy?

To minimise muscle loss during rapid weight loss on GLP-1 medications, aim for approximately 0.8 to 1.2 grams of protein per kilogram of ideal body weight daily. High-quality protein sources - such as pea protein and lean meats, may help preserve lean muscle mass and support your overall metabolic rate.

References:

1. Dervenaga, A. (2026). Metabolaid®: The Science Behind a Smarter Approach to Weight Management. [online] Nature’s Best. Available at: https://www.naturesbest.co.uk/blogs/news/metabolaid%C2%AE-the-science-behind-a-smarter-approach-to-weight-management?_pos=1&_sid=19228cca3&_ss=r  [Accessed 10 Aug. 2026].
2. Jówko, E. (2015). Green Tea Catechins and Sport Performance. [online] PubMed. Boca Raton (FL): CRC Press/Taylor & Francis. Available at: https://www.ncbi.nlm.nih.gov/books/NBK299060/  [Accessed 10 Aug. 2026].
3. Allen, R.W., Schwartzman, E., Baker, W.L., Coleman, C.I. and Phung, O.J. (2013). Cinnamon Use in Type 2 Diabetes: An Updated Systematic Review and Meta-Analysis. The Annals of Family Medicine, 11(5), pp.452–459. https://pubmed.ncbi.nlm.nih.gov/24019277/ [Accessed 10 Aug. 2026].
4. Havel, P.J. (2004). A Scientific Review: The Role of Chromium in Insulin Resistance. [online] The Diabetes Educator. Available at: https://pubmed.ncbi.nlm.nih.gov/15208835/  [Accessed 10 Aug. 2026].
5. Agraib, L.M., Islam Al-Shami, Alkhatib, B. and Hasan, H. (2024). The impact of energy releasing B-vitamin intake on indices of obesity and cardiac function: a cross-sectional study. F1000Research, 12, pp.1382–1382. doi:10.12688/f1000research.139672.3. https://pmc.ncbi.nlm.nih.gov/articles/PMC11319906/ [Accessed 10 Aug. 2026].
6. Obeagu, E.I. (2025). Iron homeostasis and health: understanding its role beyond blood health – a narrative review. Annals of Medicine & Surgery, [online] 87(6), pp.3362–3371. doi:10.1097/ms9.0000000000003100. https://pmc.ncbi.nlm.nih.gov/articles/PMC12140690/ [Accessed 10 Aug. 2026].
7. Kreider, R.B., Kalman, D.S., Antonio, J., Ziegenfuss, T.N., Wildman, R., Collins, R., Candow, D.G., Kleiner, S.M., Almada, A.L. and Lopez, H.L. (2017). International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. Journal of the International Society of Sports Nutrition, [online] 14(1). doi:10.1186/s12970-017-0173-z. https://pubmed.ncbi.nlm.nih.gov/28615996/ [Accessed 10 Aug. 2026].
8. Negro, M., Giardina, S., Marzani, B. and Marzatico, F. (2008). Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system. The Journal of Sports Medicine and Physical Fitness, [online] 48(3), pp.347–351. Available at: https://pubmed.ncbi.nlm.nih.gov/18974721/  [Accessed 10 Aug. 2026].
9. Babault, N., Païzis, C., Deley, G., Guérin-Deremaux, L., Saniez, M.-H., Lefranc-Millot, C. and Allaert, F.A. (2015). Pea proteins oral supplementation promotes muscle thickness gains during resistance training: a double-blind, randomized, Placebo-controlled clinical trial vs. Whey protein. Journal of the International Society of Sports Nutrition, 12(1), p.3. doi:10.1186/s12970-014-0064-5. https://pubmed.ncbi.nlm.nih.gov/25628520/ [Accessed 10 Aug. 2026].
10. Sabater-Molina, M., Larqué, E., Torrella, F. and Zamora, S. (2009). Dietary fructooligosaccharides and potential benefits on health. Journal of physiology and biochemistry, [online] 65(3), pp.315–28. doi:10.1007/BF03180584. https://pubmed.ncbi.nlm.nih.gov/20119826/ [Accessed 10 Aug. 2026].
11. Cleveland Clinic (2023). Probiotics. [online] Cleveland Clinic. Available at: https://my.clevelandclinic.org/health/treatments/14598-probiotics  [Accessed 10 Aug. 2026].
12. Price, C.T., Langford, J.R. and Liporace, F.A. (2012). Essential Nutrients for Bone Health and a Review of their Availability in the Average North American Diet. The Open Orthopaedics Journal, [online] 6(1), pp.143–149. doi:10.2174/1874325001206010143. https://pmc.ncbi.nlm.nih.gov/articles/PMC3330619/ [Accessed 10 Aug. 2026].
13. Volpe, S.L. (2013). Magnesium in Disease Prevention and Overall Health. Advances in Nutrition, 4(3), pp.378S-383S. doi:10.3945/an.112.003483.  https://www.sciencedirect.com/science/article/pii/S2161831322011280  [Accessed 10 Aug. 2026].